Showing posts with label treatment. Show all posts
Showing posts with label treatment. Show all posts

Wednesday, 16 July 2008

Avastin - Wet Macular Degeneration: by Donald Arson

Avastin is the brand name for Bevaciumab a monoclonal antibody or an antibody that is an identical clone of a single parent cell. It was approved in 2004 by the FDA for use in the treatment of some cancers and is used as a first or second line treatment for patients.
As the first clinically available angiogenesis inhibitor the United States it inhibits new cancer cells by blocking the growth of blood vessels in pre-existing tumors. A solid, non-liquid, tumor needs to grow additional blood vessels to be able to reach a certain size.
With an angiostatic agent such as Avastin the growth of new blood vessels is slowed stopping the cancer from growing indefinitely. It is usually given every 14 days intravenously in the arm and can be used with other drugs in combination and with intravenous 5-fluorouracilâ€"based chemotherapy.
Developed by Genentech (NYSE: DNA), a leading biotechnology corporation, it is marketed in the United States under the Genentech name and outside the US under Roche.
When it was originally available in 2004 it was only FDA approved for the treatment of many forms of small cell lung cancer and metastatic colon cancer. A metastatic cancer, in this case colon cancer, is a cancer that spreads from one part or organ to another non-adjacent part or organ.
In 2008 the FDA opened up the doors and allowed for the treatment of breast cancer. There are also clinical trials under way to use Avastin for the treatment of non-metastatic colon cancer, metastatic renal cell carcinoma, metastatic breast cancer, metastatic glioblastoma multiform, metastatic hormone-refractory prostate cancer, metastatic or unresectable locally advanced pancreatic cancer, and metastatic ovarian cancer.
Avastin is also currently being used off-label, the practice of prescribing drugs for a purpose outside the scope of the drug's approved label, for the treatment of wet macular degeneration by some retinal specialists.
Wet macular degeneration or AMD is a condition that causes loss of vision from the growth of abnormal blood vessel choriocapillaries, through Bruch's membrane. This eventually leads to blood and protein leaking below the macula, an oval spot near the middle of the retina in the human eye. With AMD rapid, often irreversible vision loss can occur through the leaking, bleeding and scaring of the blood vessels if left untreated.
Dr. Philip J Rosenfeld, MD, PhD of the Bascom Palmer Eye Institute conducted a study that showed positive results for the treatment of AMD with Avastin. According to Dr. Rosenfeld’s study Avastin improved vision in as little as one week for patients treated for AMD.
For AMD treatment Avastin is used in very low amounts by retinal specialists. They usually have a pharmacists transfer the drug from the original vile to a pre-filled needles containing single doses. The specialists will then usually treat the patient in their own office.
As with any drug it is always best to talk to your doctor or pharmacist before starting any treatment

Cancer survivors-Alternative Medicine: Is it for you?

Cancer is a multi factorial disease, involving the whole body, not only the affected part. Allopathic medicine offers a few invasive localized treatments (surgery, chemotherapy, radiation), which cause a lot of damage to the rest of the systems, while leaving the body depleted of its vitality.
Alternative medicine recognizes that cancer is not a local, individual process, but one that involves the whole body, therefore a holistic approach to treatment is used by means of herbal medicine, acupuncture and energetic medicine.
This type of medicine is practiced in many countries and is accepted at different levels, depending on varying standards of regulation. For examples, in most European countries, some MD.'s specialize in practicing natural medicine along with their allopathic methods.
Complimentary medicine(as it is often reffered to) is defined as any form of medical treatment that is different from conventional treatments. Its medicines are becoming more and more popular as their effectiveness is increasingly tested and proven for treatment. There are many different types of alternative medicine techniques in use today.
The goal of alternative medicine is to enable the body to use its own mechanisms to stimulate healing and prevent diseases from occurring.
Natural medicines are called remedies. These remedies are usually given in small doses (homeopathics), or large doses (nutrients). Practitioners work to tailor a treatment plan for each individual to gain the maximum benefits. They concentrate on the body as a whole, and not just treating the symptoms that ail the patient.
The best way of using alternative medicine is by building the body after all allopathic treatments have deleted its vitality; giving alternative medicine a try might be the best thing for your cancer recovery.