Showing posts with label research. Show all posts
Showing posts with label research. Show all posts

Tuesday, 29 July 2008

HATE CRIMES

by Donald P. Green
While conventional wisdom has been that hate crimes in the United States rise with a declining economy, an analysis of hate crime in New York City from 1987 to 1995 has found little evidence linking racial, religious, ethnic, or homophobic incidents to deteriorating economic conditions. Political scientists Donald P. Green, Ph.D., and Andrew Rich, of Yale University, and psychologist Jack Glaser, also of Yale University, conducted the research, which is published in the July issue of the American Psychological Association's (APA) Journal of Personality and Social Psychology.
In determining whether economic downturns precipitate a greater incidence of hate crimes, the authors assembled monthly hate crime statistics compiled by the New York Police Department for the boroughs of Queens, Manhattan, Brooklyn, and the Bronx and compared them with monthly unemployment rates from the U.S. Bureau of Labor Statistics. They defined hate crimes as "unlawful acts of violence, vandalism, harassment, and intimidation directed against victims on account of their putative race, religion, ethnicity, or sexual orientation." Links between unemployment rates and hate crime were examined separately for Black, Asian, Latino, gay/lesbian, Jewish, and White victim groups. In no case was there a statistical link between economic fluctuations and rates of hate crime, nor were such links found when the authors analyzed historical statistics relating cotton prices to the lynching of Blacks in the South prior to World War II.
The researchers offer two reasons that may explain why economic downturns do not lead to increases in hate crimes. The authors note that laboratory tests indicate that the effects of frustration and aggression dissipate dramatically over time. Absent an immediate target, they speculate that aggression bred by frustration may weaken before an attack occurs. The authors also point out that lynching and contemporary hate crimes tend to be group activities that require more coordination and persistence than individual acts of violence such as domestic violence. The decay of aggressive impulses may explain why economic declines coincide with increases in child abuse but not with hate crime.
Another reason why economic downturns over the past decade have not led to increased hate crimes is historical in nature. The researchers point out that political elite and organizations (such as the Ku Klux Klan) play a mediating role by attributing blame and eliciting public resentment toward minority groups in times of financial decline. The authors conclude that the relationship between economic discontent and inter-group aggression may hinge on the ways in which political leaders and organizations frame and mobilize economic grievances and societal discontent.

Saturday, 26 July 2008

Prominent Cancer Doctor Warns About Cellphones

The head of a prominent cancer research institute has warned his faculty and staff to limit cellphone use because of a possible cancer risk, The Associated Press reports.
Dr. Ronald B. Herberman, the director of the University of Pittsburgh Cancer Institute, notes that while the evidence about a cellphone-cancer link remains unclear, people should take precautions, particularly for children.
“Really at the heart of my concern is that we shouldn’t wait for a definitive study to come out, but err on the side of being safe rather than sorry later,” Dr. Herberman told The Associated Press.
Earlier this year, three prominent brain surgeons raised similar concerns while speaking on “The Larry King Show.” Their concerns were largely based on observational studies that showed only an association between cellphone use and cancer, not a causal relationship. The most important of these studies is called Interphone, a vast research effort in 13 countries, including Canada, Israel and several in Europe.
Some of the research suggests a link between cellphone use and three types of tumors: glioma; cancer of the parotid, a salivary gland near the ear; and acoustic neuroma, a tumor that essentially occurs where the ear meets the brain. All these tumors are rare, so even if cellphone use does increase risk, the risk is still very low.
On Wednesday, Dr. Herberman sent a memo to about 3,000 faculty and staff saying that children should use cellphones only for emergencies because their brains are still developing. He advised adults to keep cellphones away from the head and use the speakerphone or a wireless headset, he said.
“Although the evidence is still controversial, I am convinced that there are sufficient data to warrant issuing an advisory to share some precautionary advice on cellphone use,” he wrote in his memo.

Wednesday, 16 July 2008

Avastin - Wet Macular Degeneration: by Donald Arson

Avastin is the brand name for Bevaciumab a monoclonal antibody or an antibody that is an identical clone of a single parent cell. It was approved in 2004 by the FDA for use in the treatment of some cancers and is used as a first or second line treatment for patients.
As the first clinically available angiogenesis inhibitor the United States it inhibits new cancer cells by blocking the growth of blood vessels in pre-existing tumors. A solid, non-liquid, tumor needs to grow additional blood vessels to be able to reach a certain size.
With an angiostatic agent such as Avastin the growth of new blood vessels is slowed stopping the cancer from growing indefinitely. It is usually given every 14 days intravenously in the arm and can be used with other drugs in combination and with intravenous 5-fluorouracilâ€"based chemotherapy.
Developed by Genentech (NYSE: DNA), a leading biotechnology corporation, it is marketed in the United States under the Genentech name and outside the US under Roche.
When it was originally available in 2004 it was only FDA approved for the treatment of many forms of small cell lung cancer and metastatic colon cancer. A metastatic cancer, in this case colon cancer, is a cancer that spreads from one part or organ to another non-adjacent part or organ.
In 2008 the FDA opened up the doors and allowed for the treatment of breast cancer. There are also clinical trials under way to use Avastin for the treatment of non-metastatic colon cancer, metastatic renal cell carcinoma, metastatic breast cancer, metastatic glioblastoma multiform, metastatic hormone-refractory prostate cancer, metastatic or unresectable locally advanced pancreatic cancer, and metastatic ovarian cancer.
Avastin is also currently being used off-label, the practice of prescribing drugs for a purpose outside the scope of the drug's approved label, for the treatment of wet macular degeneration by some retinal specialists.
Wet macular degeneration or AMD is a condition that causes loss of vision from the growth of abnormal blood vessel choriocapillaries, through Bruch's membrane. This eventually leads to blood and protein leaking below the macula, an oval spot near the middle of the retina in the human eye. With AMD rapid, often irreversible vision loss can occur through the leaking, bleeding and scaring of the blood vessels if left untreated.
Dr. Philip J Rosenfeld, MD, PhD of the Bascom Palmer Eye Institute conducted a study that showed positive results for the treatment of AMD with Avastin. According to Dr. Rosenfeld’s study Avastin improved vision in as little as one week for patients treated for AMD.
For AMD treatment Avastin is used in very low amounts by retinal specialists. They usually have a pharmacists transfer the drug from the original vile to a pre-filled needles containing single doses. The specialists will then usually treat the patient in their own office.
As with any drug it is always best to talk to your doctor or pharmacist before starting any treatment